产品货号:
Z30951
中文名称:
KCNMA1抗体
英文名称:
Anti-KCNMA1 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
| 抗体名称 | Anti-KCNMA1 Antibody |
| 指标别名 | potassium calcium-activated channel subfamily M alpha 1;BKTM;CADEDS;IEG16;KCa1.1;LIWAS;MaxiK;PNKD3;SAKCA;SLO;SLO-ALPHA;SLO1;bA205K10.1;hSlo;mSLO1;KCNMA1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | KCNMA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human KCNMA1 recombinant protein (Position:K124-Q467).Human KCNMA1 shares 99% amino acid (aa) sequence identity with both mouse and rat KCNMA1. |
| 实际分子量 | 110~138KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Calcium-activated potassium channel subunit alpha-1 also known as KCa1.1,or BK channel for short,is a voltage gated potassium channel encoded by the KCNMA1 gene and characterized by their large conductance of potassium ions (K+) through cell membranes.This gene is located on 10q22.3.BK channels are activated (opened) by changes in membrane electrical potential and/or by increases in concentration of intracellular calcium ion (Ca2+).It is essential for the regulation of several key physiological processes including smooth muscle tone and neuronal excitability.BK channels also contribute to the behavioral effects of ethanol in the worm C.elegans under high concentrations (> 100mM,or approximately 0.50% BAC).It remains to be determined if BK channels contribute to intoxication in humans. |
| Uniprot ID | Q12791 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | potassium large conductance calcium-activated channel,subfamily M,alpha member 1 |
| 蛋白名全称 | Calcium-activated potassium channel subunit alpha-1 |
| 推荐稀释比 | Western blot (WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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